The introduction of UHPLC presents a slightly high hurdle, but I do want a high separation even with the HPLC under my hand now.
If you want to extract the maximum performance out of the UHPLC in separation.
And if you want to achieve high separation analysis in the reversed phase mode with 100% aqueous mobile phase.

CAPCELL CORE AQ is the most suitable for high separation analysis with 100% aqueous mobile phase.

CAPCELL CORE is a polymer-coated type core-shell column. It comprises core-shell type packing material with a 2.7-µm particle presenting a layer of 0.5-µm porous silica around a 1.7-µm solid-core. It realizes high separation not only in UHPLC but also in HPLC.

Features

Core-shell column capable of using 100% aqueous mobile phase

Continued use of 100% aqueous mobile phase is possible

With CAPCELL CORE AQ, we sought the bonding density of C₂₇ group (Heptacosyl group) appropriate for the 100 % aqueous mobile phase, yet still hydrophobic.
As a result, we achieved stable measurement with 100% aqueous mobile phase.

Good retention and separation of highly polar compounds

Compared with the C₁₈ columns, while the analysis time for hydrophobic compounds is about one half with CAPCELL CORE AQ, the retention of polar compounds is increased and the separation is good.

Thanks to the structural property of the core-shell type packing material, CAPCELL CORE AQ presents a separation capacity equivalent to that of totally porous Sub2 columns while keeping the back pressure not too high. CAPCELL CORE AQ is the most suitable for reducing time in the high-performance separation analysis of highly polar compounds with 100% aqueous mobile phase by UHPLC as well as by HPLC and in the analysis of hydrophobic compounds under conventional conditions.

Physical properties

Functional group	Particle diameter (µm)	Pore diameter (nm)	Specific surface area (m 2/g)	C%	Range of acceptable pH
Heptacosyl gropup	2.7	16	90	4	2～10