HPLC Column
Ceramospher (Chiral)
User's Manual
Ceramospher is coined from "ceramic" and "sphere." This is a completely new type of column for optical separation where the optically active metal complex Δ-Ru(phen)32+(phen=1,10-phenanthroline) is adsorbed to porous spherical ceramics by cation exchange.
The clay mineral used for the chromatographic support has a multilayer structure. Analyte molecules are supposed to enter narrow gaps between the layers, and to fit into environments where three-dimensional interactions for chiral recognition take place. When trying many chiral compounds, probability of successful optical separation is much higher than those of conventional chiral columns.
Difference between RU-1 and RU-2
RU-2 packing material is created from RU-1 by further special hydrophobic treatment. Consequently, Ceramospher (Chiral) RU-2 allows the use of aqueous (reversed phase) mobile phases.
· Excellent separation hit rate
Optimum choice, particularly for the optical separation of neutral and acidic compounds
No need to optimize conditions
Analytical conditions can be easily set by using a flowchart
· High loadability
5 to 10 times higher than that of conventional columns for optical separation
Data 1
· Excellent durability
Data 2
· Excellent pressure resistance (20 MPa)
· Stable in a wide temperature range RU-1
20 to 60°C (methanol type)
15 to 60°C (water/methanol type)
· Also available outside Japan
Property values
Type Particle size (µm) Specific surface area (m2/g) Acceptable pH Pore size (nm)
RU-1 5 300 3~6.5 4
RU-2 5 300 3~6.5 4
Page top